SGOL2 anticorps (Center)

N° du produit ABIN2795993

L’anticorps Lapin Polyclonal anti-SGOL2 a été validé pour WB. Il convient pour détecter SGOL2 dans des échantillons de Humain.

Aperçu rapide pour SGOL2 anticorps (Center) (ABIN2795993)

Antigène: SGOL2 (Shugoshin-Like 2 (SGOL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGOL2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SGOL2 anticorps

Épitope: AA 391-419, Center

Fonction: Rabbit Anti-Human SGOL2 (Center) Antibody

Immunogène: This SGOL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human SGOL2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000SGOL2 Antibody (Center) .

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur SGOL2

Antigène: SGOL2 (Shugoshin-Like 2 (SGOL2))

Autre désignation: SGOL2

Sujet:

Target Description: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

Gene Symbol: SGOL2

Poids moléculaire: 144739 Da

ID gène: 151246

UniProt: Q562F6